PF-3837
Product Specifications
CAS Number
2772910-13-9
Target
Kinesin|||Apoptosis
Related Pathways
Cytoskeletal Signaling|||Apoptosis
Bioactivity
PF-3837 is an inhibitor of the Mps1 kinase, with a Ki value of 0.33 nM and an IC50 value of 5.5 nM. It disrupts cell cycle checkpoints by inhibiting the catalytic activity of Mps1, thereby reducing genomic stability and leading to cancer cell apoptosis (Apoptosis) . PF-3837 is utilized in the study of breast cancer.
Smiles
N#CC1=CNC2=NC(=NC(NC(C)(C)CO)=C12)NC3=CC=C(N=C3C)N4CCOCC4
Molecular Formula
C21H26N8O2
Molecular Weight
422.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
46546151 3x 1.0 µg DNA
TEX28P2 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Ask
View Details 
![Human eIF4E Matched Antibody Pair Set [ABP-S-02493]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP3-28367JF525 0.1 mL
Human Monoclonal Proprotein Convertase 9/PCSK9 Antibody (lodelcizumab) [Janelia Fluor 525]
Ask
View Details