XSJ05
Product Specifications
CAS Number
1461652-87-8
Target
Topoisomerase, Apoptosis
Related Pathways
DNA Damage/DNA Repair, Apoptosis
Bioactivity
XSJ05, a derivative of camptothecin (CPT), exhibits anti-cancer activity by inhibiting topoisomerase I (Topo I) . This compound induces DNA double-strand breaks, leading to DNA damage. Furthermore, XSJ05 stifles the growth of colorectal cancer (CRC), halts the cell cycle in the G2/M phase, and induces apoptosis.
Smiles
O=C1N2C(C=3C(C2)=C(C=NNC(NC4=CC=C(C)C=C4)=S)C=5C(N3)=CC=CC5)=CC6=C1COC(=O)[C@@]6(CC)O
Molecular Formula
C29H25N5O4S
Molecular Weight
539.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2386433 100 µL
G protein beta subunit like Rabbit Polyclonal Antibody (BF647)
Sign In for Pricing
View Details 
orb2400746 100 µL
Phospho-PP2A alpha+beta (Tyr307) Rabbit Polyclonal Antibody (PerCP-Cy5.5)
Sign In for Pricing
View Details