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PROTAC PIN1 degrader-1

Product Specifications

Target

PROTACs

Related Pathways

PROTAC

Bioactivity

PROTAC PIN1 degrader-1, a targeted PROTAC for PIN1, effectively degrades PIN1 protein in MDA-MB-468 triple-negative breast cancer cells with a DC50 value of 0.018 ?M. This compound is utilized in tumor research.

Smiles

N#CC=1C=CC(=CC1)C2=CC=C(C=C2)N3N=NC(=C3)CC(NC(=O)C4(C5=NC=CC=C5C)CC4)C(=O)NC6CCN(CCCCCOC7=CC=CC=8C(=O)N(C(=O)C78)C9C(=O)NC(=O)CC9)CC6

Molecular Formula

C51H52N10O7

Molecular Weight

917.02

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/240554098116526152/T200020

CAS Number

3038591-59-9

Available Sizes

Curated Selection

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