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PCSK9-IN-29

Product Specifications

CAS Number

1233353-86-0

Target

LDLR

Related Pathways

Metabolism

Bioactivity

PCSK9-IN-29 serves as a lipid-lowering agent that enhances the expression of low-density lipoprotein receptor (LDLR) protein and reduces PCSK9 protein expression in hepG2 cells. Additionally, in crab-eating macaques on a high-fat diet, it lowers serum LDL-C, TC, and liver enzyme ALT levels, reduces body weight and fat, and boosts bone mineral content. PCSK9-IN-29 is useful for studies involving non-alcoholic fatty liver disease and obesity.

Smiles

O=S(=O)(OC=1C(OC)=CC=C2C1CN3CCC4=CC(OC)=C(OC)C=C4C3C2)C=5C=CC=C(F)C5

Molecular Formula

C26H26FNO6S

Molecular Weight

499.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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