Apicidin
Product Specifications
CAS Number
183506-66-3
Target
Autophagy, Parasite, Apoptosis, HDAC
Related Pathways
Autophagy, Apoptosis, Chromatin/Epigenetic, Microbiology/Virology, DNA Damage/DNA Repair
Purity
0.9993
Bioactivity
Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic and antiproliferative activity. It attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis and autophagy by decreasing Abeta load in APP/PS1 mice, making it a valuable tool for leukemia research.
Smiles
[H][C@]12CCCCN1C(=O)[C@@]([H])(NC(=O)[C@H](Cc1cn(OC)c3ccccc13)NC(=O)[C@H](CCCCCC(=O)CC)NC2=O)[C@@H](C)CC
Molecular Formula
C34H49N5O6
Molecular Weight
623.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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