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CGAMP disodium

Product Specifications

CAS Number

2407516-83-8

Target

Others, Endogenous Metabolite, STING

Related Pathways

Metabolism, Others, Immunology/Inflammation

Bioactivity

CGAMP disodium is a cyclic dinucleotide (CDN) found in bacteria that acts as an endogenous second messenger affecting interferon production in response to cytoplasmic DNA. cGAMP disodium cascades signals from type I interferons and other immune mediators by activating interferon gene stimulator (STING) . cGAMP disodium is a potent sublingual immune adjuvant that enables better immune function (serum anti-PA neutralization and airway secretions anti-PA SIgA response) .

Smiles

O[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])OP(O)(OC[C@]3([H])[C@@]([C@H]([C@H](N4C5=NC=NC(N)=C5N=C4)O3)O)([H])OP(O)(OC2)=O)=O)N6C7=C(C(N=C(N7)N)=O)N=C6.[Na].[Na]

Molecular Formula

C20H24N10O13P2.2Na

Molecular Weight

720.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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