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Sulindac sulfide

Product Specifications

CAS Number

49627-27-2

Target

AChR, Gamma-secretase, Raf, Drug Metabolite

Related Pathways

Neuroscience, MAPK, Stem Cells, Metabolism, Proteases/Proteasome

Purity

>99.99%

Bioactivity

Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibitor of gamma-secretase with an IC50 value of 20.2 μM. It is an active metabolite of sulinic acid.

Smiles

C(=C/1\C=2C(C(CC(O)=O)=C1C)=CC(F)=CC2)\C3=CC=C(SC)C=C3

Molecular Formula

C20H17FO2S

Molecular Weight

340.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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