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EG01377 2HCl

Product Specifications

CAS Number

2749438-61-5

Target

Complement System

Related Pathways

Immunology/Inflammation

Purity

0.9956

Bioactivity

EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.

Smiles

N=C(N)NCCC[C@@H](C(O)=O)NC(C(SC=C1)=C1NS(=O)(C2=C3C(CCO3)=CC(C4=CC=C(C=C4)CN)=C2)=O)=O.Cl.Cl

Molecular Formula

C26H32Cl2N6O6S2

Molecular Weight

659.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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