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CRA-026440 hydrochloride

Product Specifications

CAS Number

847459-98-7

Target

Apoptosis, HDAC

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair, Apoptosis

Purity

0.9978

Bioactivity

CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.

Smiles

Cl.CN(C)CCOc1ccc2[nH]c(cc2c1)C(=O)NCC#Cc1ccc(cc1)C(=O)NO

Molecular Formula

C23H25ClN4O4

Molecular Weight

456.92

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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