CRA-026440 hydrochloride
Product Specifications
CAS Number
847459-98-7
Target
Apoptosis, HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair, Apoptosis
Purity
0.9978
Bioactivity
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.
Smiles
Cl.CN(C)CCOc1ccc2[nH]c(cc2c1)C(=O)NCC#Cc1ccc(cc1)C(=O)NO
Molecular Formula
C23H25ClN4O4
Molecular Weight
456.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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