5'-O-TBDMS-dU
5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides[1].
Product Specifications
CAS Number
[76223-04-6]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-o-tbdms-du.html
Purity
96.51
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O[C@@H](C[C@H](N1C(NC(C=C1)=O)=O)O2)[C@H]2CO[Si](C)(C)C(C)(C)C
Molecular Formula
C15H26N2O5Si
Molecular Weight
342.46
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Moharram S, et, al. Design and synthesis of 3'- and 5'-O- (3-benzenesulfonylfuroxan-4-yl) -2'-deoxyuridines: biological evaluation as hybrid nitric oxide donor-nucleoside anticancer agents. J Med Chem. 2004 Mar 25;47 (7) :1840-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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