Fasnall
Fasnall is a selective fatty acid synthase (FASN) inhibitor with an IC50 of 3.71 μM. Fasnall induces apoptosis in HER2+ breast cancer cell lines. Fasnall shows potent anti-tumor activities[1].
Product Specifications
CAS Number
[929978-58-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Fatty Acid Synthase (FASN)
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fasnall.html
Purity
99.94
Solubility
DMSO : 10 mg/mL (ultrasonic; warming)
Smiles
CC1=C(C2=C(N=CN=C2S1)NC3CN(CC3)CC4=CC=CC=C4)C
Molecular Formula
C19H22N4S
Molecular Weight
338.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Yazan Alwarawrah, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2 (+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23 (6) :678-88.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
040903 200 µL
RBMS1, ID (RBMS1, C2orf12, MSSP, MSSP1, SCR2, RNA-binding motif, single-stranded-interacting protein 1, Single-stranded DNA-binding protein MSSP-1, Suppressor of CDC2 with RNA-binding motif 2)
Sign In for Pricing
View Details 
R0008-60A-ML490 100 µL
Rab8A, CT (RAB8A Member RAS Oncogene Family, Ras-associated Protein RAB8A, Ras-related Protein Rab8A, AA409338, MEL, Mel Transforming Oncogene, MGC124948, Oncogene c-Mel) (MaxLight 490) discontinued
Sign In for Pricing
View Details