Fasnall

Fasnall is a selective fatty acid synthase (FASN) inhibitor with an IC50 of 3.71 μM. Fasnall induces apoptosis in HER2+ breast cancer cell lines. Fasnall shows potent anti-tumor activities[1].

Product Specifications

CAS Number

[929978-58-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Fatty Acid Synthase (FASN)

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fasnall.html

Purity

99.94

Solubility

DMSO : 10 mg/mL (ultrasonic; warming)

Smiles

CC1=C(C2=C(N=CN=C2S1)NC3CN(CC3)CC4=CC=CC=C4)C

Molecular Formula

C19H22N4S

Molecular Weight

338.47

Precautions

H302, H315, H319, H335

References & Citations

[1]Yazan Alwarawrah, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2 (+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23 (6) :678-88.