Fasnall
Fasnall is a selective fatty acid synthase (FASN) inhibitor with an IC50 of 3.71 μM. Fasnall induces apoptosis in HER2+ breast cancer cell lines. Fasnall shows potent anti-tumor activities[1].
Product Specifications
CAS Number
[929978-58-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Fatty Acid Synthase (FASN)
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fasnall.html
Purity
99.94
Solubility
DMSO : 10 mg/mL (ultrasonic; warming)
Smiles
CC1=C(C2=C(N=CN=C2S1)NC3CN(CC3)CC4=CC=CC=C4)C
Molecular Formula
C19H22N4S
Molecular Weight
338.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Yazan Alwarawrah, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2 (+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23 (6) :678-88.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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