Monoclonal Anti-SUMO Tag
Product Specifications
Background
Small Ubiquitin-like Modifier (or SUMO) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle. SUMO proteins are similar to ubiquitin, and SUMOylation is directed by an enzymatic cascade analogous to that involved in ubiquitination. In contrast to ubiquitin, SUMO is not used to tag proteins for degradation.
Host
Mouse
Reactivity
All
Immunogen
Purified recombinant yeast SUMO.
Applications
Western Blot (1:1000-10000)
Form
Liquid
Buffer
In PBS (pH7.4), 50% Glycerol and 0.02% Sodium Azide.
References & Citations
. Hay RT (Apr 2005) . "SUMO: a history of modification". Mol. Cell 18 (1) : 1–12.
Storage Conditions
Store at -20°C for 1 year. Or aliquot and store at -80°C for long term. Avoid repeated freeze and thaw cycles.
Specificity
Detect the expression level of SUMO tag fusion proteins.
Isotype
IgG1
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
