Monoclonal Anti-c-Myc/ MycTag
Product Specifications
Background
C-Myc is a regulator gene that codes for a transcription factor. A mutated version of Myc is found in many cancers, which causes Myc to be constitutively (persistently) expressed. This leads to the unregulated expression of many genes, some of which are involved in cell proliferation and results in the formation of cancer. It may be a potential cancer drug target. c-Myc-tag is one of epitope tags, it is particularly useful for western blotting, immunofluorescence and immunoprecipitation experiments, although they also find use in antibody purification.
Host
Mouse
Reactivity
All
Immunogen
A synthetic peptideEQKLISEEDL conjugated to KLH.
Applications
Western Blot (1:1000-10000) ; Immunofluorescence, IF (1:200-1000) ; Immunoprecipitation, IP (1:100-500)
Form
Liquid
Buffer
In PBS (pH7.4), 50% Glycerol and 0.02% Sodium Azide.
References & Citations
1. Soucek L, Whitfield J, Martins CP, Finch AJ, Murphy DJ, Sodir NM, Karnezis AN, Swigart LB, Nasi S, Evan GI (October 2008) . "Modelling Myc inhibition as a cancer therapy". Nature 455 (7213) : 679–83.
Storage Conditions
Store at 2-8°C for 1 month. Or aliquot and store at -20°C or below for long term. Avoid repeated freeze and thaw cycles.
Isotype
IgG1
Curated Selection
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