Malaria Plasmodium falciparum, Pf Protein

Native plasmodium falciparum, Pf protein purified from inactivated malaria Plasmodium falciparum cell culture supernatant.

Product Specifications

Background

Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.The parasite is transmitted through the bite of a female Anopheles mosquito and causes the disease's most dangerous form, falciparum malaria. It is responsible for around 50% of all malaria cases.P. falciparum is therefore regarded as the deadliest parasite in humans. It is also associated with the development of blood cancer (Burkitt's lymphoma) and is classified as Group 2A carcinogen.

Source

Inactivated Malaria Plasmodium falciparum cell culture supernatant.

Applications

Calibrator or standard in Immunoassays

Purity

>95% by SDS-PAGE

Buffer

Each vial contains 0.01 M PBS (pH7.8) and 0.1% Proclin 300.

References & Citations

Rich, S. M.; Leendertz, F. H.; Xu, G.; Lebreton, M.; Djoko, C. F.; Aminake, M. N.; Takang, E. E.; Diffo, J. L. D.; Pike, B. L.; Rosenthal, B. M.; Formenty, P.; Boesch, C.; Ayala, F. J.; Wolfe, N. D. (2009) . "The origin of malignant malaria". Proceedings of the National Academy of Sciences. 106 (35) : 14902–14907. Perkins, D. J.; Were, T.; Davenport, G. C.; Kempaiah, P.; Hittner, J. B.; Ong'Echa, J. M. (2011) . "Severe malarial anemia: Innate immunity and pathogenesis". International Journal of Biological Sciences. 7 (9) : 1427–1442. Perlmann, P; Troye-Blomberg, M (2000) . "Malaria blood-stage infection and its control by the immune system". Folia Biologica. 46 (6) : 210–8.