Monoclonal Anti-Cortisol
Product Specifications
Background
Cortisol, known more formallyas Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal cortex. It is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. It plays an important role in glycogenolysis, the breaking down of glycogen to glucose-1-phosphate and glucose, in liver and muscle tissue. It also decreases bone formation. Various synthetic forms of cortisol are used to treat a variety of diseases.
Host
Mouse
Applications
ELISA; Western Blot, WB; , WB
Purity
>95% by HPLC & SDS-PAGE
Form
Liquid
Buffer
Protein A or G purified and supplied in 0.01 M PBS (pH7.2)
References & Citations
1. Scott E (2011-09-22) . "Cortisol and Stress: How to Stay Healthy". About.com. Retrieved 2011-11-29. 2. Hoehn K, Marieb EN (2010) . Human Anatomy & Physiology. San Francisco: Benjamin Cummings.
Storage Conditions
Aliquot and store at -20°C for 2 years. Avoid repeated freeze and thaw cycles.
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