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Monoclonal Anti-Interleukin 1 receptor-like 1, IL1RL1/ST2 (DetectionAb)

Product Specifications

Background

Interleukin 1 receptor-like 1, also known as IL1RL1 and ST2, is a protein that in humans is encoded by the IL1RL1 gene.ST2 is a member of the interleukin 1 receptor family. The ST2 protein has two isoforms and is directly implicated in the progression of cardiac disease: a soluble form (referred to as soluble ST2 or sST2) and a membrane-bound receptor form (referred to as the ST2 receptor or ST2L) .

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human IL-1RL1/ST2 Protein.

Capture Antibody

Capture Ab:ST2mAb (clone # 1A9) ; Detection Ab:ST2mAb (clone #2E5)

Clone

2E5

Applications

ELISA; Chemilumineseent immunoassay, CLIA

Purity

>95% by HPLC & SDS-PAGE

Form

Liquid

Buffer

Protein A or G purified and supplied in 0.9% NaClwithout preservative.

References & Citations

1. "Entrez Gene: IL1RL1 interleukin 1 receptor-like 1" Tominaga S, Yokota T, Yanagisawa K, Tsukamoto T, Takagi T, Tetsuka T (December 1992) . "Nucleotide sequence of a complementary DNA for human ST2". Biochim. Biophys. Acta. 1171 (2) : 215–8. 2. Dale M, Nicklin MJ (April 1999) . "Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q". Genomics. 57 (1) : 177–9.

Storage Conditions

Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Isotype

IgG1

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