Monoclonal Anti-Prostate-specific antigen, PSA (Capture or DetectionAb)
Product Specifications
Background
Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.
Host
Mouse
Reactivity
Human
Immunogen
Recombinant prostate specific antigen protein.
Capture Antibody
PSA #3D7 PSA #2G2 PSA #2G2 PSA #3D7 PSA #1C2 PSA #3D7 PSA #3D7 PSA #1C2
Clone
3D7
Applications
ELISA; Chemilumineseent immunoassay, CLIA
Purity
>95% by HPLC & SDS-PAGE
Form
Liquid
Buffer
Protein A or G purified and supplied in 0.9% NaClwithout preservative.
References & Citations
1. Balk SP, Ko YJ, Bubley GJ (Jan 2003) . "Biology of prostate-specific antigen". Journal of Clinical Oncology. 21 (2) : 383–91. 2. Hellstrom WJG, ed. (1999) . "Chapter 8: What is the prostate and what is its function?". American Society of Andrology Handbook. San Francisco: American Society of Andrology.
Storage Conditions
Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Isotype
IgG1
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