Monoclonal Anti-Prostate-specific antigen, PSA (Capture or DetectionAb)

Product Specifications

Background

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.

Host

Mouse

Reactivity

Human

Immunogen

Recombinant prostate specific antigen protein.

Capture Antibody

PSA #3D7 PSA #2G2 PSA #2G2 PSA #3D7 PSA #1C2 PSA #3D7 PSA #3D7 PSA #1C2

Clone

1C2

Applications

ELISA; Chemilumineseent immunoassay, CLIA

Purity

>95% by HPLC & SDS-PAGE

Form

Liquid

Buffer

Protein A or G purified and supplied in 0.9% NaClwithout preservative.

References & Citations

1. Balk SP, Ko YJ, Bubley GJ (Jan 2003) . "Biology of prostate-specific antigen". Journal of Clinical Oncology. 21 (2) : 383–91. 2. Hellstrom WJG, ed. (1999) . "Chapter 8: What is the prostate and what is its function?". American Society of Andrology Handbook. San Francisco: American Society of Andrology.