Monoclonal Anti-Cancer embryonic antigen, CEA (Capture or DetectionAb)
Product Specifications
Background
Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Therefore, CEA is usually present only at very low levels in the blood of healthy adults. However, the serum levels are raised in some types of cancer, which means that it can be used as a tumor marker in clinical tests. Serum levels can also be elevated in heavy smokers.
Host
Mouse
Reactivity
Human
Immunogen
Recombinant CEAprotein
Capture Antibody
Capture Ab:Clone # E8 or Clone #C8 ; Detection Ab:Clone # C8 or Clone #E8
Clone
E8
Applications
ELISA; Chemilumineseent immunoassay, CLIA
Purity
>95% by HPLC & SDS-PAGE
Form
Liquid
Buffer
Protein A or G purified and supplied in 0.9% NaClwithout preservative.
References & Citations
1. Duffy, Michael J. (2001-04-01) . "Carcinoembryonic Antigen as a Marker for Colorectal Cancer: Is It Clinically Useful?". Clinical Chemistry. 47 (4) : 624–630.
Storage Conditions
Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Isotype
IgG1
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