Monoclonal Anti-AFP (Detection Ab)

Product Specifications

Background

Alpha-fetoprotein (AFP, α-fetoprotein; also sometimes called alpha-1-fetoprotein, alpha-fetoglobulin, or alpha fetal protein) is a protein that in humans is encoded by the AFP gene. The AFP gene is located on the q arm of chromosome 4 (4q25) . Biological response evaluation by the measurement of serial AFP levels is a useful predictor of overall survival and intrahepatic remote recurrence after RFA. Therefore, an initial AFP response may aid in determining the need of closer follow-up as a therapeutic response indicator of RFA.

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Alpha fetal protein (AFP) protein.

Capture Antibody

Capture Ab:AFPmAb (clone # A1) ; Detection Ab:AFPmAb (clone # C3)

Clone

Applications

ELISA; Chemilumineseent immunoassay, CLIA

Purity

>95% by HPLC & SDS-PAGE

Form

Liquid

Buffer

Protein A or G purified and supplied in0.9% NaClwithout preservative.

References & Citations

1. Yu SJ, Kwon JH, Kim W, Yoon JH, Lee JM, Lee JY, Cho EJ, Lee JH, Kim HY, Jung YJ, Kim YJ.Initial Alpha-Fetoprotein Response Predicts Prognosis in Hepatitis B-related Solitary HCC Patients After Radiofrequency Ablation. J Clin Gastroenterol. 2017 Aug 8.