Monoclonal Anti- ZFP-42 / REX1 antibody

Zfp-42 (Rex1) is a known marker ofHYPERLINK "http://en.wikipedia.org/wiki/Pluripotency" \o "Pluripotency"pluripotency, and most notably found in undifferentiatedHYPERLINK "http://en.wikipedia.org/wiki/Embryonic_stem_cell" \o "Embryonic stem cell"embryonic stem cells. It is a 288-amino acid protein and has a calculated molecular mass of 32.3 kD.[1]It has been identified in theHYPERLINK "http://en.wikipedia.org/wiki/Testicles" \o "Testicles"testicles, expressed at theHYPERLINK "http://en.wikipedia.org/wiki/Spermatocytes" \o "Spermatocytes"spermatocytesin the more inner layers of the testicles. Rex1 has been found to be critically important in maintaining proliferative state in mesenchymal stem cells (MSC), while simultaneously preventing differentiation.

Hosler, B. A., LaRosa, G. J., Grippo, J. F., Gudas, L. J. Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells. Molec. Cell. Biol. 9: 5623-5629, 1989.