Recombinant Human IL-1F10 Protein

Recombinant Human IL-1F10 is produced by the E.coli system, with the target gene encoding Met1-Trp152 expressed.

Product Specifications

Background

Interleukin-1 family member 10 is a protein that in humans is encoded by the IL1F10 gene.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported.

Synonyms

IL1F10, FIL1-theta, IL-1HY2, IL-38, IL1-theta, IL1HY2, FKSG75, interleukin 1 family member 10 (theta), interleukin 1 family member 10

Source

E.coli

Applications

SDS-PAGE

Endotoxin

<1 EU/µg by LAL test

Purity

>95%by SDS-PAGE

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 6.0.

Reconstitution

Dissolve the lyophilized protein in distilled water (It is not recommended to reconstitute to a concentration<100μg/ml.)

References & Citations

Bensen JT, Dawson PA, Mychaleckyj JC, Bowden DW (Dec 2001) . "Identification of a novel human cytokine gene in the interleukin gene cluster on chromosome 2q12-14". J Interferon Cytokine Res. 21 (11) : 899–904. Taylor SL, Renshaw BR, Garka KE, Smith DE, Sims JE (May 2002) . "Genomic organization of the interleukin-1 locus". Genomics. 79 (5) : 726–33. Nicklin MJ, Barton JL, Nguyen M, FitzGerald MG, Duff GW, Kornman K (May 2002) . "A sequence-based map of the nine genes of the human interleukin-1 cluster". Genomics. 79 (5) : 718–25.