Recombinant Human IL-1F10 Protein
Recombinant Human IL-1F10 is produced by the E.coli system, with the target gene encoding Met1-Trp152 expressed.
Product Specifications
Background
Interleukin-1 family member 10 is a protein that in humans is encoded by the IL1F10 gene.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported.
Synonyms
IL1F10, FIL1-theta, IL-1HY2, IL-38, IL1-theta, IL1HY2, FKSG75, interleukin 1 family member 10 (theta), interleukin 1 family member 10
Source
E.coli
Applications
SDS-PAGE
Endotoxin
<1 EU/µg by LAL test
Purity
>95%by SDS-PAGE
Buffer
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 6.0.
Reconstitution
Dissolve the lyophilized protein in distilled water (It is not recommended to reconstitute to a concentration<100μg/ml.)
References & Citations
Bensen JT, Dawson PA, Mychaleckyj JC, Bowden DW (Dec 2001) . "Identification of a novel human cytokine gene in the interleukin gene cluster on chromosome 2q12-14". J Interferon Cytokine Res. 21 (11) : 899–904. Taylor SL, Renshaw BR, Garka KE, Smith DE, Sims JE (May 2002) . "Genomic organization of the interleukin-1 locus". Genomics. 79 (5) : 726–33. Nicklin MJ, Barton JL, Nguyen M, FitzGerald MG, Duff GW, Kornman K (May 2002) . "A sequence-based map of the nine genes of the human interleukin-1 cluster". Genomics. 79 (5) : 718–25.
Storage Conditions
Shipat 4°C. Upon receipt, aliquot and store at -20°Cor -80°C for long term. Avoid repeated freeze and thaw cycles.
Formulation
Lyophilized
Uniprot Accession Number
AAI03967.1
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