Recombinant Human TGF-beta 1 Protein

Recombinant human TGF-beta 1 is produced by the mammalian system, with the target gene encoding Ala279-Ser390 expressed.

Product Specifications

Background

Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. In humans, TGF-β1 is encoded by the TGFB1 gene.

Synonyms

TGFB1, CED, DPD1, LAP, TGFB, TGFbeta, transforming growth factor beta 1, IBDIMDE, TGF-beta1

Source

CHO Stable Cells

Applications

SDS-PAGE

Endotoxin

<0.01EU/µg by LAL test

Purity

>95%by SDS-PAGE

Buffer

Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl,150mMNaCl,4%Mannitol, pH 2.5.

Reconstitution

Dissolve the lyophilized protein in distilled water (It is not recommended to reconstitute to a concentration<100μg/ml.)

References & Citations

Ghadami M, Makita Y, Yoshida K, Nishimura G, Fukushima Y, Wakui K, et al. (January 2000) . "Genetic mapping of the Camurati-Engelmann disease locus to chromosome 19q13.1-q13.3". American Journal of Human Genetics. 66 (1) : 143–147. Vaughn SP, Broussard S, Hall CR, Scott A, Blanton SH, Milunsky JM, et al. (May 2000) . "Confirmation of the mapping of the Camurati-Englemann locus to 19q13. 2 and refinement to a 3.2-cM region". Genomics. 66 (1) : 119–121.