Recombinant Human TGF-beta 1 Protein
Recombinant human TGF-beta 1 is produced by the mammalian system, with the target gene encoding Ala279-Ser390 expressed.
Product Specifications
Background
Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. In humans, TGF-β1 is encoded by the TGFB1 gene.
Synonyms
TGFB1, CED, DPD1, LAP, TGFB, TGFbeta, transforming growth factor beta 1, IBDIMDE, TGF-beta1
Source
CHO Stable Cells
Applications
SDS-PAGE
Endotoxin
<0.01EU/µg by LAL test
Purity
>95%by SDS-PAGE
Buffer
Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl,150mMNaCl,4%Mannitol, pH 2.5.
Reconstitution
Dissolve the lyophilized protein in distilled water (It is not recommended to reconstitute to a concentration<100μg/ml.)
References & Citations
Ghadami M, Makita Y, Yoshida K, Nishimura G, Fukushima Y, Wakui K, et al. (January 2000) . "Genetic mapping of the Camurati-Engelmann disease locus to chromosome 19q13.1-q13.3". American Journal of Human Genetics. 66 (1) : 143–147. Vaughn SP, Broussard S, Hall CR, Scott A, Blanton SH, Milunsky JM, et al. (May 2000) . "Confirmation of the mapping of the Camurati-Englemann locus to 19q13. 2 and refinement to a 3.2-cM region". Genomics. 66 (1) : 119–121.
Storage Conditions
Shipat 4°C. Upon receipt, aliquot and store at -20°Cor -80°C for long term. Avoid repeated freeze and thaw cycles.
Formulation
Lyophilized
Uniprot Accession Number
P01137
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