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Recombinant Rat CD68 Protein

Recombinant human CD68 Protein with a polyhistidine tag at the C-terminus

Product Specifications

Background

CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia) .Human CD68 is a Type I transmembrane glycoprotein, heavily glycosylated in its extracellular domain, with a molecular weight of 110 kD. Its primary sequence consists of 354 amino acids with predicted molecular weight of 37.4 kD if it were not glycosylated.

Synonyms

GP110, LAMP4, SCARD1, Cluster of Differentiation 68

Source

HEK293 Cells

Applications

SDS-PAGE

Endotoxin

<1.0 EU per μg of the protein as determined by the LAL method

Purity

>95% by SDS-PAGE

Buffer

Lyophilized from sterile PBS, pH 7.4.

References & Citations

Holness CL, Simmons DL (March 1993) . "Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins". Blood. 81 (6) : 1607–13. "CD68 - Macrosialin precursor - Homo sapiens (Human) - CD68 gene & protein".

Storage Conditions

Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Formulation

Lyophilized

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