Recombinant Human Leptin Protein
Recombinant human Leptinprotein with his tag at N-terminal with molecular weight of 19 kDa.
Product Specifications
Background
Leptin, the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin modulates reproductive activity but its potential influence on LH secretion from anterior pituitary (AP) cells during implantation period in pigs (days 14-16 of pregnancy) remained unexplored.Potentially harmful changes in cardiovascular-risk parameters, markedly reduced subcutaneous fat and unchanged ectopic fat during TRT and a reduction in adiponectin levels. On the other hand, the decrease in leptin and leptin:adiponectin ratio assessments could reflect an amelioration of the cardiovascular-risk profile linked to hyperleptinaemia in aging men with T2D.
Synonyms
Leptin, LEP, OB, OBS, LEP, Obesity factor, Obese protein
Source
E. Coli Rosetta DE3
Applications
SDS-PAGE; ELISA
Purity
>90%by SDS-PAGE
Buffer
Each vial contains500mM NaCl, purified by Ni column.
References & Citations
Siawrys G, Gajewska A.In vitro effect of leptin on anterior pituitary cells LH secretory activity during early pregnancy in pig. Pol J Vet Sci. 2017 Mar 28;20 (1) :67-76. Magnussen LV, Andersen PE, Diaz A, Ostojic JM, Højlund K, Hougaard DM, Christensen AN, Nielsen TL, Andersen MS.MR-spectroscopy of hepatic-fat and adiponectin and leptin levels during testosterone therapy in type 2 diabetes. A randomized, double-blinded, placebo-controlled trial. Eur J Endocrinol. 2017 May 18. pii: EJE-17-0071.
Storage Conditions
Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
Formulation
Liquid
Available Sizes
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