Recombinant Human Leptin Protein

Leptin, the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin modulates reproductive activity but its potential influence on LH secretion from anterior pituitary (AP) cells during implantation period in pigs (days 14-16 of pregnancy) remained unexplored.Potentially harmful changes in cardiovascular-risk parameters, markedly reduced subcutaneous fat and unchanged ectopic fat during TRT and a reduction in adiponectin levels. On the other hand, the decrease in leptin and leptin:adiponectin ratio assessments could reflect an amelioration of the cardiovascular-risk profile linked to hyperleptinaemia in aging men with T2D.

Siawrys G, Gajewska A.In vitro effect of leptin on anterior pituitary cells LH secretory activity during early pregnancy in pig. Pol J Vet Sci. 2017 Mar 28;20 (1) :67-76. Magnussen LV, Andersen PE, Diaz A, Ostojic JM, Højlund K, Hougaard DM, Christensen AN, Nielsen TL, Andersen MS.MR-spectroscopy of hepatic-fat and adiponectin and leptin levels during testosterone therapy in type 2 diabetes. A randomized, double-blinded, placebo-controlled trial. Eur J Endocrinol. 2017 May 18. pii: EJE-17-0071.