Cardiac Troponin T Protein (Active)

Recombinant full length human cardiac Troponin T protein.

Product Specifications

Background

Troponin T is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle, the others are troponin I and troponin C. Troponin T was discovered by the German physician Hugo A. Katus. It binds to tropomyosin and helps position it on actin And in a less complicated light, Troponin T modulates contraction of striated muscle. In patients with stable coronary artery disease, troponin T concentrations have been found to be significantly associated with the incidence of cardiovascular death and heart failure, but not with myocardial infarction.

Synonyms

Troponin T, cardiac muscle, TnTc, Cardiac muscle Troponin T, cTnT, TNNT2

Source

E. Coli

Applications

ELISA; SDS-PAGE

Purity

>96% by SDS-PAGE

Buffer

Each vial contains 5 mM EDTA, 15 mM Mercaptoethanol, 20 mM Tris with 0.5% NaN3.

References & Citations

"A Sensitive Cardiac Troponin T Assay in Stable Coronary Artery Disease". New England Journal of Medicine. 2009.

Storage Conditions

Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Formulation

Liquid