NT-proBNP Protein (Active)
Recombinant full length human NT-proBNP protein.
Product Specifications
Background
The N-terminal prohormone of brain natriuretic peptide (NT-proBNP) is a 76 amino acid N-terminal fragment of brain natriuretic peptide.Both BNP and NT-proBNP levels in the blood are used for screening, diagnosis of acute congestive heart failure (CHF) and may be useful to establish prognosis in heart failure, as both markers are typically higher in patients with worse outcome.BNP may be a useful screening tool for left ventricular dysfunction in patients with history suggestive of heart disease and be used to assist in forming a pretest probability, which in turn could greatly assist in appropriateness of patient referral and in optimization of drug therapy.
Source
E. Coli
Applications
WB; ELISA
Purity
>95% by SDS-PAGE
Buffer
Each vial contains 0.01 M PBS (pH7.5) without preservatives.
References & Citations
1.Bhalla V, Willis S, Maisel AS (2004) . "B-type natriuretic peptide: the level and the drug--partners in the diagnosis of congestive heart failure". Congest Heart Fail 10 (1 Suppl 1) : 3–27. 2. Atisha D, Bhalla MA, Morrison LK, Felicio L, Clopton P, Gardetto N, Kazanegra R, Chiu A, Maisel AS (September 2004) . "A prospective study in search of an optimal B-natriuretic peptide level to screen patientsfor cardiac dysfunction".Am. Heart J.148 (3) : 518–23.
Storage Conditions
Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
Formulation
Liquid
Curated Selection
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