HBeAg Protein
Recombinant full length human Hepatitis BeAg protein.
Product Specifications
Background
HBeAg is the extracellular form of HBcAg (Hepatitis B viral protein, core antigen), hence why the presence of both are markers of viral replication, and antibodies to these antigens are markers of a decline in replication. Multiple protein products can be produced from the same DNA sequence. When "ORF Core" and "Pre C" are translated together, the result is "HBeAg". Both HBeAg and HBcAg are made from the same reading frame, but HBeAg is secreted from cells and accumulates in serum as an immunologically distinct soluble antigen. HBeAg is secreted and found in the serum of patients and serves as a marker of active replication in chronic hepatitis.
Synonyms
HBeAg, Hepatitis BeAg
Source
E. Coli
Applications
ELISA
Purity
>90% by SDS-PAGE
Buffer
Each vial contains 0.02 M sodium phosphate (pH7.2) with 0.02% sodium azide.
References & Citations
Kimura T, Rokuhara A, Matsumoto A, et al. (May 2003) . "New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA". J. Clin. Microbiol. 41 (5) : 1901–6.
Storage Conditions
Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
Formulation
Liquid
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