PROTAC PTPN2 degrader-1
PROTAC PTPN2 degrader-1 (compound example 77) is a potent PTPN2 degrader. PROTAC PTPN2 degrader-1 has the potential for the research of cancer or metabolic disease[1].
Product Specifications
CAS Number
[2655638-07-4]
UNSPSC
12352005
Target
Phosphatase; PROTACs
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/protac-ptpn2-degrader-1.html
Purity
95.01
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CC1=CC=C(C2=CC(N(C)C(N3C4C(NC(CC4)=O)=O)=O)=C3C=C2)C=C1)NC5=CC6=CC(O)=C(N7CC(NS7(=O)=O)=O)C(F)=C6C=C5
Molecular Formula
C33H27FN6O8S
Molecular Weight
686.67
References & Citations
[1]Gesine Kerstin Veits, et al. Protein tyrosine phosphatase degraders and methods of use thereof. WO2021127586A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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