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PROTAC PTPN2 degrader-1

PROTAC PTPN2 degrader-1 (compound example 77) is a potent PTPN2 degrader. PROTAC PTPN2 degrader-1 has the potential for the research of cancer or metabolic disease[1].

Product Specifications

CAS Number

2655638-07-4

UNSPSC

12352005

Target

Phosphatase; PROTACs

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; PROTAC

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/protac-ptpn2-degrader-1.html

Purity

95.01

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CC1=CC=C(C2=CC(N(C)C(N3C4C(NC(CC4)=O)=O)=O)=C3C=C2)C=C1)NC5=CC6=CC(O)=C(N7CC(NS7(=O)=O)=O)C(F)=C6C=C5

Molecular Formula

C33H27FN6O8S

Molecular Weight

686.67

References & Citations

[1]Gesine Kerstin Veits, et al. Protein tyrosine phosphatase degraders and methods of use thereof. WO2021127586A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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