Anti-CD49f Purified
CD49f (alpha 6 integrin) is a type I transmembrane glycoprotein, which noncovalently associates with CD29 (beta 1 integrin) to form VLA-6, and with CD104 (beta 4 integrin) to form alpha6/beta4 integrin complex. CD49f is expressed on platelets, megakaryocytes, monocytes, T cells and thymocytes. It is widely expressed on many cultured adherent cell lines and on epithelia in non-lymphoid tissues. It is important for adhesion to laminins, invasin, and merosin, hence also for cell migration, embryogenesis, metastasis, formation of hemidesmosomes in epithelia, and other processes.
Product Specifications
Certification
RUO
Immunogen
Mouse mammary tumor cells
Target Antigen
CD49f
Clone
GoH3
Applications
FC (QC tested), ICC, IP, IHC-F
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
The rat monoclonal antibody GoH3 recognizes an extracellular epitope of CD49f, an alpha6 integrin subunit.
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Species
Non-human primates, Horse, Pig, Rabbit, Cow, Dog, Cat, Human, Sheep, Mouse
CAS Number
9007-83-4
Isotype
Rat IgG2a
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items