Recombinant human VAMP-8 protein
Vehicle-associated membrane (VAMP8), also known as endobrevin, is the main components of a SNARE complex involved in the docking and fusion of synaptic vesicles with the presynaptic membrane. This protein plays a role in regulated enzyme secretion in pancreatic acinar cells and is involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. It is required for dense-granule secretion in platelets. Recombinant VAMP8 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
10.9 kDa (96aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Polgar J., et al. (2002) Blood. 100 (3) :1081-3.; ; Ren Q., et al. (2007) Mol Biol Cell. 18 (1) :24-33;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.5) containing 0.1mM PMSF, 0.2M NaCl, 50% glycerol, 0.1M Imidazole
Scientific Category
Neuroscience
NCBI Accession Number
NP_003752
Uniprot Accession Number
Q9BV40
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MEEASEGGGN DRVRNLQSEV EGVKNIMTQN VERILARGEN LEHLRNKTED LEATSEHFKT TSQKVARKFW WKNVKM
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
