Recombinant human Thioredoxin-2 protein
Thioredoxin (Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The Thioredoxin2 may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Recombinant Thioredoxin2 was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Specifications
Product Name Alternative
MTRX, TRX2, MT-TRX, Thioredoxin2, mitochondrial thioredoxin, thioredoxin 2 precursor, Thioredoxin mitochondrial, TRX 2, TXN 2, TXN2, Thioredoxin-2
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
Enzyme Activity, SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Bioactivity
Molecular Weight
11 kDa (108aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wang Z., et al. (2007) . Rapid Commun Mass Spectrom. 21 (22) :3658-66.; ; Zhang H., et al. (2007) . Arch Biochem biophys. 465 (1) :119-26.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Scientific Category
Redox Proteins
NCBI Accession Number
NP_036605
Uniprot Accession Number
Q99757
Species
Human
AA Sequence
MTTFNIQDGP DFQDRVVNSE TPVVVDFHAQ WCGPCKILGP RLEKMVAKQH GKVVMAKVDI DDHTDLAIEY EVSAVPTVLA MKNGDVVDKF VGIKDEDQLE AFLKKLIG
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