Recombinant human Survivin protein
Survivin is a human gene that is part of the inhibitor of apoptosis family (IAP) . The Survivin protein functions to inhibit caspase activation therefore leading to negative regulation of apoptosis or programmed cell death. Recombinant human Survivin fused to CaM-tag at N-terminus was expressed in E. coli and purified by conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
Calmodulin Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
33 kDa (294aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wolanin., et al. (2007) . Postepy Biochem. 53 (1) :10-8.; ; O'Driscoll L., et al. (2003) Curr Cancer Drug Targets. 3 (2) :131-52.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl
Scientific Category
Cancer
NCBI Accession Number
AAH34148.1
Uniprot Accession Number
O15392
Species
Human
AA Sequence
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
