Recombinant human Retinol Binding Protein 4/RBP4 protein

Retinol binding protein 4 (RBP4) belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. This protein was found to be expressed and secreted by adipose tissue, and was strongly associated with insulin resistance. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. Recombinant human RBP4 was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Plasma retinol-binding protein, PRBP, RBP

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

21 kDa (184aa) confirmed by MALDI-TOF

Additionnal Information

RBP4, Retinol binding protein 4, RBP4, Retinol binding protein 4, Retinol binding protein 4 Plasma retinol binding protein 4, prbp, PRO2222, Retinol binding protein 4 interstitial, Retinol binding protein 4 plasma, RBP0701-10 µg, RBP0701-20 µg, RBP0701-50 µg, RBP0701-100 µg, RBP0701-250 µg, RBP0701-500 µg, RBP0701-1 mg, RBP0701-10, RBP0701-20, RBP0701-50, RBP0701-100, RBP0701-250, RBP0701-500, RBP0701-1

References & Citations

Yao-Borengasser A., et al. (2007) J Clin Endocrinol Metab. 92 (7) :2590-7.; ; McTernan PG., et al. (2007) J Clin Endocrinol Metab. 92 (7) :2430-2.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_006735.2

Uniprot Accession Number

P02753

Species

Human

AA Sequence

MERDCRVSSF RVKENFDKAR FSGTWYAMAK KDPEGLFLQD NIVAEFSVDE TGQMSATAKG RVRLLNNWDV CADMVGTFTD TEDPAKFKMK YWGVASFLQK GNDDHWIVDT DYDTYAVQYS CRLLNLDGTC ADSYSFVFSR DPNGLPPEAQ KIVRQRQEEL CLARQYRLIV HNGYCDGRSE RNLL