Recombinant drosophila melanogaster GAGA-POZ protein

The GAGA factor is a sequence-specific DNA-binding protein, which participates in the regulation of the expression of a variety of different classes of genes in Drosophila such as many developmentally regulated genes, stress induced genes, and cell cycle regulated genes, as well as housekeeping genes. GAGA contains a C-terminal glutamine-rich domain and a highly conserved N-terminal POZ domain which reported to be involved in self-oligomerization in a number of other POZ domain containing proteins. In case of GAGA protein, the N-terminal POZ domain mediates the formation of oligomers both in vitro and in vivo. GAGA-POZ domain was overexpressed in E. coli and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

Trithorax-like isoform A, Trl, Adf-2, GAGA, Nc70F, TFGAGA, GAGA-POZ domain, Trithorax-like protein, GAGA factor, GAF, Adh transcription factor 2, Neural conserved at 70F, Transcription factor GAGA, Trithorax-like isoform A, Trithorax like protein

Expression System

E.coli

Antigen Species

Drosophila melanogaster

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

14 kDa (130aa) confirmed by MALDI-TOF

Additionnal Information

GAGA-POZ, POZ3001-10 µg, POZ3001-20 µg, POZ3001-50 µg, POZ3001-100 µg, POZ3001-250 µg, POZ3001-500 µg, POZ3001-1 mg, POZ3001-10, POZ3001-20, POZ3001-50, POZ3001-100, POZ3001-250, POZ3001-500, POZ3001-1

References & Citations

Kosoy A., et al. (2002) J Biol.Chem. 277 (44), 42280-8.; ; Espinas ML., et al. (1999) J Biol. Chem. 274 (23),16461-9.; ; Farkas G., et al. (1994) Nature 371, 806-808.;