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Recombinant human Podoplanin/PDPN protein

Podoplanin (PDPN) is a small mucin-like transmembrane protein, widely expressed in various specialized cell types throughout the body. This is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. Recombinant human PDPN protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography techniques.

Product Specifications

Product Name Alternative

TIA2, T1A, T1 ALPHA GENE, T1 alpha, Podoplanin, PDPN, PA2.26 antigen, OTTHuMP00000044504, OTTHuMP00000009640, OTS8, Lung type I cell membrane-associated glycoprotein isoform a, Lung type I cell membrane associated glycoprotein isoform a AGGRuS, Lung type I cell membrane associated glycoprotein, hT1alpha2, hT1alpha1, HT1A-1, GP40, Gp38, GP36, Glycoprotein 36 KD

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

13.4 kDa (130aa) confirmed by MALDI-TOF

Additionnal Information

Podoplanin, PDPN, Lung type-I cell membrane-associated glycoprotein isoform a, T1A, GP36, GP40, Gp38, OTS8, T1A-2, HT1A-1, PA2.26, Lung type-I cell membrane-associated glycoprotein isoform a, Podoplanin, PDPN, Lung type-I cell membrane-associated glycoprotein isoform a AGGRuS, Glycoprotein 36 KD, Glycoprotein 36, gp 36, GP 38, GP 40, GP40, HT1A 1, HT1A1, hT1alpha1, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein isoform a, hT1alpha2, PA2.26 antigen, T1 alpha, Lung type I cell membrane associated glycoprotein T1A 2, OTS 8, OTTHuMP00000009640, OTTHuMP00000044504, T1 ALPHA GENE, TIA 2, TIA2., PDP0801-10 µg, PDP0801-20 µg, PDP0801-50 µg, PDP0801-100 µg, PDP0801-250 µg, PDP0801-500 µg, PDP0801-1 mg, PDP0801-10, PDP0801-20, PDP0801-50, PDP0801-100, PDP0801-250, PDP0801-500, PDP0801-1

References & Citations

Wicki A., et al. (2006) Br J Cancer. 96 (1) :1-5.; ; Zimmer G., et al. (1999) Biochem J. 341, 277-84.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl

Scientific Category

Cancer

NCBI Accession Number

NP_006465

Uniprot Accession Number

Q86YL7

Species

Human

AA Sequence

MASTGQPEDD TETTGLEGGV AMPGAEDDVV TPGTSEDRYK SGLTTLVATS VNSVTGIRIE DLPTSESTVH AQEQSPSATA SNVATSHSTE KVDGDTQTTV EKDGLSTVTL

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