Recombinant human Podoplanin/PDPN protein
Podoplanin (PDPN) is a small mucin-like transmembrane protein, widely expressed in various specialized cell types throughout the body. This is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. Recombinant human PDPN protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
13.4 kDa (130aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wicki A., et al. (2006) Br J Cancer. 96 (1) :1-5.; ; Zimmer G., et al. (1999) Biochem J. 341, 277-84.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl
Scientific Category
Cancer
NCBI Accession Number
NP_006465
Uniprot Accession Number
Q86YL7
Species
Human
AA Sequence
MASTGQPEDD TETTGLEGGV AMPGAEDDVV TPGTSEDRYK SGLTTLVATS VNSVTGIRIE DLPTSESTVH AQEQSPSATA SNVATSHSTE KVDGDTQTTV EKDGLSTVTL
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