Recombinant human LAIR1 protein
LAIR-1 is a glycoprotein (~32kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. The extracellular domain of LAIR-1 (22-125aa) was overexpressed in E. coli, and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
11.7 kDa (105aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Sathish JG., et al. (2001) J Immunol. 166 (3) :1763-70.; ; Meyaard L., et al. (1999) J. Immunol. 162, 5800-4.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 50 mM NaCl, 1mM EDTA
Scientific Category
Immunology
NCBI Accession Number
NP_002278
Uniprot Accession Number
Q6GTX8
Species
Human
AA Sequence
MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPS ESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
BCMA Protein, Human, Recombinant (ECD, hFc Tag)
S100 Calcium Binding Protein A13 (S100A13) (NM_005979) Human Tagged ORF Clone Lentiviral Particle
Human Capping Protein Muscle Z Line Beta (CAPZb) ELISA Kit
Human Capping Protein Muscle Z Line Beta (CAPZb) ELISA Kit