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Recombinant human HSBP1 protein

Heat shock factor binding protein 1 (HSBP1) is a 76 amino acid protein that binds to heat shock factor 1 (HSF1), which is a transcription factor involved in the HS response. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulated HSF1 DNA-binding activity. This protein was overexpressed in E. coli and was purified to apparent homogeneity by using conventional column chromatography techniques.

Product Specifications

Product Name Alternative

Heat shock factor binding protein 1, NPC-A-13, HSF1BP, Nasopharyngeal carcinoma-associated antigen 13, NPC-A-13, Heat shock factor-binding protein 1, Heat shock factor binding protein 1, Nasopharyngeal carcinoma associated antigen 13, NPC A 13, NPCA 13

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

8.5 kDa (76aa) confirmed by MALDI-TOF

Additionnal Information

HSBP1, Heat shock factor binding protein 1, NPC-A-13, HSF1BP, Nasopharyngeal carcinoma-associated antigen 13, NPC-A-13, Heat shock factor-binding protein 1, Heat shock factor binding protein 1, Nasopharyngeal carcinoma associated antigen 13, NPC A 13, NPCA 13, HSB3001-10 µg, HSB3001-20 µg, HSB3001-50 µg, HSB3001-100 µg, HSB3001-250 µg, HSB3001-500 µg, HSB3001-1 mg, HSB3001-10, HSB3001-20, HSB3001-50, HSB3001-100, HSB3001-250, HSB3001-500, HSB3001-1

References & Citations

Morimoto, R.I., et al. (1997) Essays Biochem. 32,17-29.; ; Satyal, S.H., et al. (1998) Genes Dev. 12 (13) 1962-1974.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing, 50 mM NaCl, 20% glycerol

Scientific Category

Heat Shock Proteins

NCBI Accession Number

NP_001528.1

Uniprot Accession Number

O75506

Species

Human

AA Sequence

MAETDPKTVQ DLTSVVQTLL QQMQDKFQTM SDQIIGRIDD MSSRIDDLEK NIADLMTQAG VEELESENKI PATQKS

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