Recombinant human PLA2G16 protein
The HRAS like-suppressor 3 (HRASLS3) belongs to a class II tumor suppressor gene family and is involved in the regulation of differentiation and survival. This protein is expressed in several human tumors including ovarian carcinomas, lung carcinomas and may be involved in interferon-dependent cell death. Recombinant HRAS-like suppressor 3 was expressed in E. coli and was purified by conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
14.9 kDa (133aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Nazarenko I., et al. (2006) Am. J. Pathol. 169 (4) : 1427-39.; ; Nazarenko I., et al. (2007) J. Cell. Sci. 120: 1393-404.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0)
Scientific Category
Cancer
NCBI Accession Number
NP_001121675
Uniprot Accession Number
P53816
Species
Human
AA Sequence
MRAPIPEPKP GDLIEIFRPF YRHWAIYVGD GYVVHLAPPS EVAGAGAASV MSALTDKAIV KKELLYDVAG SDKYQVNNKH DDKYSPLPCS KIIQRAEELV GQEVLYKLTS ENCEHFVNEL RYGVARSDQV RDV
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