What is the catalog number for Recombinant human Growth Hormone 1/GH1 protein?

The catalog number for Recombinant human Growth Hormone 1/GH1 protein is GRH3001-500.

What sizes are available for Recombinant human Growth Hormone 1/GH1 protein?

Recombinant human Growth Hormone 1/GH1 protein is available in the following size(s): 500 µg.

Is Recombinant human Growth Hormone 1/GH1 protein in stock?

Recombinant human Growth Hormone 1/GH1 protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human Growth Hormone 1/GH1 protein

Human growth hormone (hGH, somatotropin), a protein hormone from the anterior lobe of the pituitary gland, comprises a single polypeptide chain of 191 amino acid residues. The growth hormone amino acid sequence varies considerably between species, and non-primate growth hormones have little activity in man. Its main function is the stimulation of somatic and bone growth, as well as an increase in the size and mass of organs and tissues. Recombinant human growth hormone (rhGH) was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Product Specifications

Specifications

Human Growth Hormon Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range ≤ 0.2 ng/mL.

Product Name Alternative

GH, GH1, GHN, GH-N, Growth hormone, Growth hormone 1, hGH-N, Pituitary growth hormone, Somatotropin

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE, Bioactivity

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Bioactivity

Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range ≤ 0.2 ng/mL.

Molecular Weight

22.2 kDa (192aa) confirmed by MALDI-TOF

Additionnal Information

GH, GH 1, GH1, GHN, GH-N, Growth Hormone, Growth hormone 1, hGH-N, Pituitary growth hormone, Somatotropin, GRH3001-10 µg, GRH3001-20 µg, GRH3001-50 µg, GRH3001-100 µg, GRH3001-250 µg, GRH3001-500 µg, GRH3001-1 mg, GRH3001-010, GRH3001-020, GRH3001-050, GRH3001-100, GRH3001-250, GRH3001-500, GRH3001-01M

References & Citations

Wickens., et al. (1978) J. Biol Chem. 253 (7) :2483-2495; ; Goeddel. et al. (1979) Proc. Natl. Acad. Sci. 76:106-110; ; Chang, et al. (1978) Nature 275:617-624 ; ; ullrich. et al. (1977) Science 196:1313-1319.;

Other References

Lee EN, et al. Stabilizing peptide fusion for solving the stability and solubility problems of therapeutic proteins. Pharm Res. 2005 Oct;22 (10) :1735-46. {https://pubmed.ncbi.nlm.nih.gov/16180132/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) 88mM mannitol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_000506

Uniprot Accession Number

P01241

Species

Human

AA Sequence

MFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFEEAYIPKE QKYSFLQNPQ TSLCFSESIP TPSNREETQQ KSNLELLRIS LLLIQSWLEP VQFLRSVFAN SLVYGASDSN VYDLLKDLEE GIQTLMGRLE DGSPRTGQIF KQTYSKFDTN SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC GF