Recombinant human GMF-gamma protein
Glia maturation factor gamma (GMF-gamma) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. Also Glia maturation factor is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMF-gamma possesses hematopoietic tissue-specific gene expression, a promoter concentrated with high-score hematopoiesis-specific transcription factors, and possible molecular coevolution with a rudimentary blood/immune system. Recombinant human GMF-gamma protein, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Glia maturation factor gamma, Glia maturation factor, gamma, Glia maturation factor, gamma GMF GAMMA, MGC126867
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
16.8 kDa (142aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Skinner MK., et al. (2008) Mol Reprod Dev. 75 (9) :1457-72; ; Ko HS., et al. (2000) J Biochem. 127 (3) :517-23;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 1mM EDTA, 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_004868
Uniprot Accession Number
O60234
Species
Human
AA Sequence
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