What is the catalog number for Recombinant human DDIT-3/CHOP protein?

The catalog number for Recombinant human DDIT-3/CHOP protein is GAD0801-020.

What sizes are available for Recombinant human DDIT-3/CHOP protein?

Recombinant human DDIT-3/CHOP protein is available in the following size(s): 20 µg.

Is Recombinant human DDIT-3/CHOP protein in stock?

Recombinant human DDIT-3/CHOP protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human DDIT-3/CHOP protein

GADD153, also known as DNA-damage-inducible transcript 3 (DDIT3), is a basic domain-leucine zipper (bZIP) transcription factor of C/EBP family. This protein has been shown to be up-regulated by several stresses, such as amino acid or glucose starvation, endoplasmic reticulum (ER) stress, osmotic stress and hypoxia. GADD153 protein may play a role in ER stress-mediated apoptosis and in disease including diabetes, brain ischemia and neurodegenerative disease. Recombinant GADD153 fused with His-tag, was expressed in E. coli and purified by conventional chromatography techniques.

Product Specifications

Product Name Alternative

DNA damage-inducible transcript 3 protein, C/EBP zeta, CEBPZ, C/EBP-homologous protein, CHOP, C/EBP-homologous protein 10, CHOP-10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA damage-inducible protein GADD153

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

21.3 kDa (189aa) confirmed by MALDI-TOF

Additionnal Information

GADD153, Growth arrest-and DNA damage-inducible gene 153, CHOP, DDIT3, CEBPZ, CHOP10, MGC4154, Growth arrest-and DNA damage-inducible gene 153, GADD153, Growth arrest-and DNA damage-inducible gene 153 C/EBP homologous protein, C/EBP Homology Protein, CHOP 10, DDIT 3, DNA Damage Inducible Transcript 3, GADD 153, Growth Arrest and DNA Damage Inducible Protein 153, GAD0801-10 µg, GAD0801-20 µg, GAD0801-50 µg, GAD0801-100 µg, GAD0801-250 µg, GAD0801-500 µg, GAD0801-1 mg, GAD0801-10, GAD0801-20, GAD0801-50, GAD0801-100, GAD0801-250, GAD0801-500, GAD0801-1

References & Citations

Oyadomari S. and Mori M., et al. (2004) Cell death and differentiation,11: 381-389.; ; Robert M. Silva., et al: (2005) Journal of Neurochemistry ; ;95 (4) :974-986.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol

Scientific Category

Cell Cycle

NCBI Accession Number

NP_004074

Uniprot Accession Number

P35638

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MAAESLPFSF GTLSSWELEA WYEDLQEVLS SDENGGTYVS PPGNEEEESK IFTTLDPASL AWLTEEEPEP AEVTSTSQSP HSPDSSQSSL AQEEEEEDQG RTRKRKQSGH SPARAGKQRM KEKEQENERK VAQLAEENER LKQEIERLTR EVEATRRALI DRMVNLHQA