Recombinant human FABP6 protein
FABP-6 is a cytosolic protein that binds bile acids with a high affinity. In the small intestine, its expression is restricted to the ileum where it is involved in the enterohepatic circulation of bile acids. Alternate transcription promoters generate two transcript variants, encoding a 128 aa and a 177 aa residue protein. Human FABP6 isoform 2 contains 128 amino acid residues and is believed to be acetylated on Ala2. It binds both fatty acids and bile acids and has roles in fatty acid transport and metabolism. Recombinant human FABP-6 was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
14 kDa (128aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Ohmachi T., et al. (2006) . Clin Cancer Res. Sep 1; ; 12 (17) :5090-5.; ; Grober J., et al. (1999) J Biol Chem. Oct 15; ; 274 (42) :29749-54.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cell Cycle
NCBI Accession Number
AAH22489
Uniprot Accession Number
P51161
Species
Human
AA Sequence
MAFTGKFEME SEKNYDEFMK LLGISSDVIE KAHNFKIVTE VQQDGQDFTW SQHYYGGHTM TNKFTVGKES NIQTMGGKTF KATVQMEGGK LVVNFPNYHQ TSEIVGDKLV EVSTIGGVTY ERVSKRLA
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