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Recombinant human GRO gamma/CXCL3 protein

CXCL3/GROg is a small cytokine belonging to the CXC chemokine family. CXCL3 controls migration and adhesion of monocytes and mediates it effects on its target cell by interacting with a cell surface chemokine receptor called CXCR2. Recombinant human CXCL3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

C-X-C motif chemokine ligand 3, C-X-C motif chemokine 3, GRO-gamma 1-73, Growth-regulated protein gamma, GRO-gamma, Macrophage inflammatory protein 2-beta, MIP2-beta, GRO3, GROG, SCYB3, GRO3 oncogene, CINC-2b

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

10.1 kDa (94aa) confirmed by MALDI-TOF

Additionnal Information

CXCL3, GRO g, Chemokine (C-X-C motif) ligand 3, Chemokine (C-X-C motif) ligand 3, CINC-2b, GRO3, GROg, MIP2B, SCYB3, CXCL3/GRO gamma, Chemokine (C-X-C motif) ligand 3 Chemokine (CXC motif) ligand 3, Cinc 2, Cinc2, CINC2b, CXCL 3, CXCL3, Cytokine induced neutrophil chemoattractant 2, Dcip1, GRO3 oncogene, Dendritic cell inflammatory protein 1, Gm1960, GROG, Growth regulated protein gamma, Macrophage inflammatory protein 2 beta precursor, Melanoma growth stimulatory activity gamma, MGSA gamma, MIP 2b, MIP2B, SCYB3., CXC0902-10 µg, CXC0902-20 µg, CXC0902-50 µg, CXC0902-100 µg, CXC0902-250 µg, CXC0902-500 µg, CXC0902-1 mg, CXC0902-10, CXC0902-20, CXC0902-50, CXC0902-100, CXC0902-250, CXC0902-500, CXC0902-1

References & Citations

Bieche I., et al. (2007) . Endocr Relat Canter. 14 (4) :1039-52; ; Rainard P., et al. (2008) . Mol Immunol. 45 (15) :4020-7; ; Furuichi., et al. (2008) . Front biosci. 13:4021-8;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_002081

Uniprot Accession Number

P19876

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MASVVTELRC QCLQTLQGIH LKNIQSVNVR SPGPHCAQTE VIATLKNGKK ACLNPASPMV QKIIEKILNK GSTN

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