Recombinant mouse Crystallin alpha B/CRYAB protein
Alpha crystallins are composed of two gene products, alpha-A and alpha-B for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) . They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. CRYAB is expressed widely in many tissues and organs. Recombinant CRYAB was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Crya2, Crya-2, Cryab, Crystallin alpha B, HspB5
Expression System
E.coli
Antigen Species
Mouse
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
20kDa (175aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10 % glycerol
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_034094.1
Uniprot Accession Number
P23927
Species
Mouse
AA Sequence
Frequently Asked Questions
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